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six% placebo). The topics A part of the research had been Adult males aged 35 to fifty nine with serum cholesterol levels above 265 mg/dL and no prior history of cardiovascular disease. It isn't crystal clear to what extent these conclusions may be extrapolated to females and also other segments with the hypercholesterolemic inhabitants (see also PRECAUTIONS, Carcinogenesis, Mutagenesis, Impairment of Fertility).
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Cholesterol is most likely the only precursor of bile acids. All through typical digestion, bile acids are secreted to the intestines.
Other occasions (not essentially drug linked) noted in clients taking cholestyramine resin contain:
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The commonest adverse response is constipation. When used as being a cholesterol-lowering agent, predisposing factors for most issues of constipation are superior dose and increased age (in excess of sixty several years old).
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Prevalite® (cholestyramine for oral suspension, USP) powder could be practical to decreased LDL cholesterol in individuals who even have hypertriglyceridemia, but It isn't indicated where by hypertriglyceridemia would be the abnormality of most issue.